Oral Diseases – Institute of Research and Advanced Training in Health Sciences and Technologies

GROUP LEADER | MAJOR INTERESTS | RESEARCH TEAM | CURRENT PROJECTS | RELEVANT PUBLICATIONS

Header for oral pathology

GROUP LEADER
Corsina Velazco Henriques | ORCID

MAJOR INTERESTS
We are investigating the causes of diseases affecting the structures of the teeth, in a goal to improve treatment, prevention and control of the patient.

Specifically we aim at:

characterizing the periodontal disease and infectious agents
designing a new oral scale in patients with periodontal disease
detecting Helicobacter pylori in samples from subjects with and without periodontitis by appropriate Molecular Biology methods.
Identifying the genetic basis of developmental absence of maxillary lateral incisors

RESEARCH TEAM

Volunteer
João Lobo | joao.lobo@saude.cespu.pt | ORCID
José Lopes | lopes_sa@hotmail.com |

CURRENT PROJECTS

Project AMlaser-CESPU-2016: In vivo evaluation of the antimicrobial effect of the Nd: YAG laser versus sodium hypochlorite in endodontic pathogens. | PI: Cristina Coelho | Team: Cristina Coelho, Ana Manuela Azevedo, Sofia Carreira | Funding Entity: CESPU | Period covered: 04-2016 to 03-2017

Project Orto-Agenesias-CESPU-2016: Stability of orthodontic treatment in malocclusions in general and dental agenesis in particular. | PI: Teresa Pinho | Team: Teresa Pinho, Maria Paço, Ligia Rocha, Asela Conde, Joana Tavares, Rita Raposo, Ana Filipa Gomes, Filomena Dias, Selma Pascoal, Daniela Paiva, Sofia Rosas, Diogo Mendes Joana Ribas, Tomás Ribeiro, Joana Garcêz, Primavera Santos, Teresa Vale, Ana Paula Lobo, Joaquim Moreira, Maria João Calheiros Lobo | Funding Entity: CESPU | Period covered: 04-2016 to 03-2017

Project DCAORI-CESPU-2016: Design and construction of a new “attachment” used in oral rehabilitation over implants. | PI: José Manuel Mendes | Team: José Manuel Mendes, António Sérgio Silva, Carlos Aroso, ARminda Santos, Juliana de Sá, Luís Neves, Lethicia Souza, Margarida Marques, Helena Miranda, Joana Alves | Funding Entity: CESPU | Period covered: 04-2016 to 03-2017

Project MVOS-CESPU-2016: Microbiological validation of an oral health scale of infectious-inflammatory potential through 16S rDNA metagenomic techniques. | PI: Marta Relvas | Team: Marta Relvas, Corsina Velazco Henriques, Inmaculada Tomás, José Júlio Pacheco, Cristina Cabral, Filomena Salazar | Funding Entity: CESPU | Period covered: 04-2016 to 03-2017

Project DTM-CESPU-2016: Temporomandibular disorders: Interrelationship between craniocervical posture, malocclusion, psychological factors and determinants of migraine. | PI: Teresa Pinho | Team: Teresa Pinho, Maria Paço, Paula Chaves, Daniela Simões, Sofia Lopes, Filipe Duarte, David Matos, José Carlos Rocha, Vera Almeida, José Alberto Coelho, José Pereira-Monteiro, Carolina Lemos, Miguel Alves-Ferreira, Alda Sousa, Sara Valinhas, Sofia Rosas, José Alberto Duarte, CArlos Bellot Arcís, Cristina Cespedes, Josep Ustrell | Funding Entity: CESPU | Period covered: 04-2016 to 03-2017

Projet title: Helicobacter pylori detection in samples from subjects with and without periodontitis from North of Portugal.
Project Reference: 03-GCD-CICS 2011
Projet abstract: Helicobacter pylori is an actual bacteria on gastrointestinal pathology, associated to gastritis, peptic ulcer and, in particular conditions, to gastric cancer. There is still the question of the origin of infection, stomach? oral cavity, linked to periodontal disease? The purpose of this study is to detect the bacteria in saliva of individuals with and without periodontal disease optimizing appropriate molecular biology methods
Funding Entity: CESPU
Period covered: from 05-2011 to 06-2015
Leader: Corsina Velazco Henriques
Research Team: José Júlio Pacheco, Cristina Coelho, Marta Relvas, Filomena Salazar, Paolo De Marco, José Lopes, Maria José Gonçalves

Project title: Susceptibility of agenesis of lateral maxillary incisors: a study of association with candidate genes.
Project Reference: 01-GCD-CICS-2011
Project abstract: Our aim was to study a large number of genes encoding either transcription factors or key components in signaling pathways shown to be involved in tooth odontogenesis.We selected 8 genes—MSX1, PAX9, AXIN2, EDA, SPRY2, TGFA, SPRY4, and WNT10A—and performed one of the largest case-control studies taking into account the number of genes and variants assessed, aiming at the identification of MLIA susceptibility factors.
Project Reference: 01-GCD-CICS-2011
Funding Entity: CESPU
Period covered: from 05-2011 to 06-2015
Leader: Teresa Pinho
Research Team: Alda Maria Botelho Correia Sousa, Asela Lavall Conde, Carolina Luísa Cardoso Lemos, Isabel Alonso, Selma Pascoal, Miguel Fernando Alves Ferreira

Project title: The effects of manual therapy and therapeutic exercise on cervical and temporomandibular joint in individuals submitted to orthodontic treatment: a retrospective and prospective study.
Project Reference: 01-GCD-CICS-2011
Project abstract: The objective of this study is to evaluate the effectiveness of controlled and standardized protocols of physiotherapy in individuals who were subject to orthodontic treatment. A retrospective study will be held, comparing the clinical and radiographical features of subjects before and after the orthodontic treatment, in relation to muscular and articular outcomes. After this, a double-blind randomized controlled trial will be set, in order to evaluate the effectiveness of physiotherapy.
Funding Entity: CESPU
Period covered: from 05-2011 to 06-2015
Leader: Teresa Pinho
Research Team: António Angeja, Primavera Sousa-Santos, José Alberto Duarte, Maria Paço, Daniela Paiva

RELEVANT PUBLICATIONS

Fernández-Ferrer L, Montiel-Company JM, Pinho T, Almerich-Silla JM, Bellot-Arcís C

.2015

. Effects of mandibular setback surgery on upper airway dimensions and their influence on obstructive sleep apnoea - a systematic review. (Journal Article)

J Craniomaxillofac Surg, 43 (2), pp. 248–253.DOI: 10.1016/j.jcms.2014.11.017.